Why You Should Prioritize Leg Training Before Upper Body — Especially for Health & Longevity

prioritize leg day leg workouts before upper body strength training for glucose control metabolic benefits of leg day

The Case for Lower-Body Dominance

When it comes to structuring your workouts, many lifters start with what they enjoy most—and for many, that’s upper body day. But research-backed programming shows that prioritizing lower-body strength training can offer far more systemic benefits, especially for overall metabolism, hormonal function, and even glucose regulation.

Here’s why your legs should lead the way:

1. Your Legs Contain the Largest Muscles in Your Body

The glutes, quads, and hamstrings represent some of the largest and most powerful muscles in the human body. Engaging these muscle groups first in a session ensures maximum energy and output is devoted to movements that create the most systemic benefit.

Training Tip: Compound movements like squats, lunges, and deadlifts activate the entire posterior chain, forcing your body to adapt faster than isolated upper-body work.

2. Increased Energy Expenditure & Calorie Burn

Because of the sheer muscle mass involved, leg training demands greater oxygen consumption and metabolic output. This translates to:

  • More calories burned during your session

  • Higher post-exercise oxygen consumption (EPOC), aka the “afterburn” effect

This makes leg day a potent tool for fat loss and metabolic conditioning.

insulin sensitivity exercise best workout order for strength leg day benefits

3. Enhances Glucose Uptake and Insulin Sensitivity

This is where leg training really shines from a healthspan perspective.

According to studies published in the Journal of Applied Physiology and Diabetes Care, resistance training for large muscle groups improves insulin sensitivity and promotes glucose uptake more efficiently than upper-body training alone.

This has critical benefits for:

  • Individuals with sedentary lifestyles

  • Desk workers with pre-diabetic markers

  • Clients struggling with mid-day energy crashes

Clinical Evidence: One study found that just 12 weeks of leg-focused resistance training reduced fasting insulin by 24% in previously sedentary adults (Smutok et al., 1993).

4. Stimulates Anabolic Hormone Release

Training your legs leads to elevated release of:

  • Testosterone

  • Human Growth Hormone (HGH)

  • IGF-1 (Insulin-like Growth Factor)

These hormones don’t just build leg muscle — they support muscle development across your entire body, making your chest and arm days more effective later in the week.

MYOS Premier Private Training blog personal trainer Bay Area strength training structure

Bottom Line

If you're chasing long-term results — whether it's improved performance, metabolic health, fat loss, or hormonal balance — it starts from the ground up.

→ Want to restructure your training week to lead with lower body? [Book a strategy session with MYOS here]

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